This table shows the list known insiders, and is generated automatically from filings disclosed to the SEC. In addition to the names, most recent title, and director, officer, or 10% owner designation, we provide the latest disclosed holdings.
| Name | Shares | Options |
|---|---|---|
| CROOKE STANLEY T | 704,950 | 0 |
| PARSHALL B LYNNE | 704,950 | 0 |
| Chang Carmen See Note 2 | 645,105 | 0 |
| Florence Anthony A. Jr. See Note 2 | 645,105 | 0 |
| Makhzoumi Mohamad See Note 2 | 645,105 | 0 |
| Growth Equity Opportunities V, LLC | 645,105 | 0 |
| Behbahani Ali See Note 2 | 645,105 | 0 |
| MAKOWER JOSHUA See Note 2 | 645,105 | 0 |
| Sonsini Peter W. See Note 2 | 645,105 | 0 |
| Walker Paul Edward See Note 2 | 645,105 | 0 |
| BASKETT FOREST See Note 2 | 645,105 | 0 |
| SANDELL SCOTT D See Note 2 | 645,105 | 0 |
| ISIS PHARMACEUTICALS INC | 517,317 | 0 |
| ALNYLAM PHARMACEUTICALS, INC. | 489,671 | 0 |
| BARRIS PETER J See Note 2 | 205,245 | 0 |
| MOTT DAVID M See Note 2 | 205,245 | 0 |
| PAPADOPOULOS STELIOS | 118,987 | 0 |
| RASTETTER WILLIAM H WILLIAM H RASTETTER TTEE INVESTMENT 2002 TRUST U/A DTD 11/11/2002 | 62,462 | 0 |
| Hagan Joseph P | 41,700 | 0 |
| RASTETTER WILLIAM H WILLIAM H RASTETTER TTEE INVESTMENT TRUST 2002 TRUST BOARDS U/A DATED 11/11/2002 | 35,000 | 0 |
| WRIGHT TIMOTHY MICHAEL | 27,472 | 0 |
| RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 9-2-2010 | 15,422 | 0 |
| Drygin Denis | 10,000 | 0 |
| RASTETTER WILLIAM H William H. Rastetter TTEE Investment 2002 Trust Boards U/A dated 11/11/2002 | 10,000 | 0 |
| XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | 8,021 | 0 |
| Chevallard Daniel R. | 7,787 | 0 |
| Aker Christopher Ray | 4,175 | 0 |
| Witz Pascale | 3,784 | 0 |
| Collier Kathryn J | 2,759 | 0 |
| FOLETTA MARK G | 1,000 | 0 |
| XANTHOPOULOS KLEANTHIS G | 370 | 0 |
| Greene Barry E | 0 | 0 |
| RASTETTER WILLIAM H The Rastetter Family Trust dtd 9-2-2010 | 0 | 0 |
| BASKETT FOREST See Note 1 | 0 | 0 |
| ASTRAZENECA PLC | 0 | 0 |
| Huang Alice Shih-hou | 0 | 0 |
| Nunn Jason Raleigh | 0 | 0 |
| RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | 0 | 0 |
| Deeg Mark Albert | 0 | 0 |
| RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 09-02-2010 | 0 | 0 |
| Hagan Joseph P PENSCO TRUST CO OBO JOSEPH HAGAN IRA | 0 | 0 |
| Hagan Joseph P Securities purchased through an affiliated investment entity | 0 | 0 |
| Puttagunta Chetan See Note 1 | 0 | 0 |
| Behbahani Ali See Note 1 | 0 | 0 |
| RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trust | 0 | 0 |
| Szekeres David Leslie | 0 | 0 |
| Menzel Garry E | 0 | 0 |
| MARAGANORE JOHN | 0 | 0 |
| Sarissa Capital Master Fund II LP | 0 | 0 |
| Sonsini Peter W. See Note 1 | 0 | 0 |
| MAKOWER JOSHUA See Note 1 | 0 | 0 |
| SANDELL SCOTT D See Note 1 | 0 | 0 |
| CARTER BRUCE L A | 0 | 0 |
| Simeonidis Simos | 0 | 0 |
| Chang Carmen See Note 1 | 0 | 0 |
| RASTETTER WILLIAM H Rastetter Family Trust dated 9-2-2010 | 0 | 0 |
| BALTIMORE DAVID | 0 | 0 |
| Simeonidis Simos By Sarissa Capital | 0 | 0 |
| Huang Alice Shih-hou By Spouse | 0 | 0 |
| RASTETTER WILLIAM H | 0 | 0 |
| Hagan Joseph P PACIFIC PREMIER TRUST OBO JOSEPH P. HAGAN IRA | 0 | 0 |
| Sarissa Capital Offshore Master Fund LP | 0 | 0 |
| Walker Paul Edward See Note 1 | 0 | 0 |
| GRINT PAUL C | 0 | 0 |
| Florence Anthony A. Jr. See Note 1 | 0 | 0 |
| Rosen Hugh | 0 | 0 |
| 0 | 0 | |
| WILLIAMS DOUGLAS E | 0 | 0 |
| MOTT DAVID M See Note 1 | 0 | 0 |
| BARRIS PETER J See Note 1 | 0 | 0 |
| Menzel Garry E By the Garry E. Menzel and Mary E. Henshall Family Trust | 0 | 0 |
| ASTRAZENECA AB | 0 | 0 |
| DENNER ALEXANDER J | 0 | 0 |
| Makhzoumi Mohamad See Note 1 | 0 | 0 |
| BVF PARTNERS L P/IL | 0 | 0 |
| Gibson Neil W | 0 | 0 |
| Sanofi | 0 | 0 |
| RASTETTER WILLIAM H The Rastetter Family Trust DTD 9-2-2010 | 0 | 0 |
| Viswanathan Ravi See Note 1 | 0 | 0 |
| Sakoda Jon See Note 1 | 0 | 0 |
| CALSADA CRISPINA | 0 | 0 |
While Insider sales are normal part of tax harvesting and is part of compensation of executives - A large number of transactions would indicate that the management isnt convinced that the price will go up and hence reducing their holding. This would be a possible indicator or fall in price
| Name | Shares | Price | Date |
|---|
Insider buys arent usual, since it indicates a high conviction by the management that they believe the price will go up eventually. Usually a good sign that investors should consider this as a factor to purchase a stock, especially if the current SP is lower than the price the management bought these at. The table below doesnt include any Stock Options or RSUs. They're just open market purchases by the insiders.
| Name | Shares | Price | Date |
|---|