| Avoro Capital Advisors LLC |
6,800,000
|
24.33 |
| Deep Track Capital, LP |
6,500,000
|
24.33 |
| Redmile Group, LLC |
4,205,206
|
24.33 |
| Braidwell Lp |
3,714,672
|
24.33 |
| Geode Capital Management, Llc |
2,587,857
|
24.33 |
| PRHSX - T. Rowe Price Health Sciences Fund, Inc.
This fund is a listed as child fund of Price T Rowe Associates Inc /md/ and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
2,506,232
|
24.33 |
| PRNHX - T. Rowe Price New Horizons Fund, Inc.
This fund is a listed as child fund of Price T Rowe Associates Inc /md/ and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
2,254,900
|
24.33 |
| Capital International Investors |
2,164,099
|
24.33 |
| SMCWX - SMALLCAP WORLD FUND INC Class A |
2,164,099
|
24.33 |
| Yiheng Capital Management, L.P. |
2,143,497
|
24.33 |
| Soleus Capital Management, L.P. |
2,127,043
|
24.33 |
| Holocene Advisors, LP |
1,996,476
|
24.33 |
| Avidity Partners Management LP |
1,869,200
|
24.33 |
| Armistice Capital, Llc |
1,836,000
|
24.33 |
| Logos Global Management LP |
1,520,000
|
24.33 |
| Samlyn Capital, Llc |
1,517,783
|
24.33 |
| Deerfield Management Company, L.p. (series C) |
1,504,578
|
24.33 |
| PFM Health Sciences, LP |
1,465,483
|
24.33 |
| Polar Capital Holdings Plc |
1,362,001
|
24.33 |
| QUASX - AB Small Cap Growth Portfolio Class A |
1,329,106
|
23.10 |
| Deutsche Bank Ag\ |
1,281,928
|
24.33 |
| Balyasny Asset Management Llc |
1,202,733
|
24.33 |
| JATTX - Janus Henderson Triton Fund Class T |
1,196,042
|
24.33 |
| Charles Schwab Investment Management Inc |
977,454
|
24.33 |
| JAGLX - Janus Henderson Global Life Sciences Fund Class T |
975,712
|
24.33 |
| Sofinnova Investments, Inc. |
905,982
|
24.33 |
| Barclays Plc |
813,800
|
0.02 |
| Barclays Plc |
813,800
|
0.02 |
| Jpmorgan Chase & Co |
782,096
|
24.33 |
| Finepoint Capital LP |
723,600
|
24.33 |
| TimesSquare Capital Management, LLC |
719,825
|
0.03 |
| Great Point Partners Llc |
694,009
|
24.33 |
| Bank Of America Corp /de/ |
613,355
|
24.33 |
| PRDSX - T. Rowe Price QM U.S. Small-Cap Growth Equity Fund
This fund is a listed as child fund of Price T Rowe Associates Inc /md/ and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
557,606
|
24.33 |
| JAVTX - Janus Henderson Venture Fund Class T |
534,779
|
24.33 |
| CGOAX - Columbia Small Cap Growth Fund I Class A |
494,549
|
20.78 |
| Westfield Capital Management Co Lp |
476,721
|
24.33 |
| Federated Hermes, Inc. |
470,000
|
24.33 |
| Wellington Management Group Llp |
442,355
|
24.33 |
| Lombard Odier Asset Management (Switzerland) SA |
413,115
|
24.33 |
| Duquesne Family Office LLC |
400,000
|
0.03 |
| FBIOX - Biotechnology Portfolio
This fund is a listed as child fund of Fmr Llc and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
356,209
|
20.78 |
| Artisan Partners Limited Partnership |
311,121
|
24.33 |
| THCGX - Thornburg Core Growth Fund - Class A |
291,337
|
24.33 |
| Thornburg Investment Management Inc |
291,337
|
0.02 |
| 5AM Venture Management, LLC |
284,626
|
24.33 |
| AVCIX - Vp Capital Appreciation Fund Class I
This fund is a listed as child fund of American Century Companies Inc and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
282,619
|
24.33 |
| Rhenman & Partners Asset Management AB |
280,000
|
23.77 |
| PSOPX - JPMorgan Small Cap Value Fund Class I |
264,321
|
24.33 |
| Ally Bridge Group (NY) LLC |
255,310
|
24.33 |
| Pier Capital, LLC |
231,162
|
24.33 |
| Td Asset Management Inc |
223,218
|
24.33 |
| Ikarian Capital, LLC |
213,521
|
24.33 |
| Twinbeech Capital Lp |
204,435
|
24.33 |
| ARTJX - Artisan International Small-Mid Fund Investor Shares |
193,931
|
24.33 |
| PHSTX - PUTNAM GLOBAL HEALTH CARE FUND Class A Shares |
191,507
|
20.78 |
| Monarch Partners Asset Management LLC |
186,706
|
21.41 |
| EAM Global Investors LLC |
178,456
|
24.33 |
| J. Goldman & Co LP |
176,543
|
24.33 |
| Ghost Tree Capital, LLC |
175,000
|
24.33 |
| Moore Capital Management, Lp |
171,241
|
24.33 |
| Lord, Abbett & Co. Llc |
169,710
|
0.02 |
| Walleye Capital LLC |
143,578
|
24.33 |
| Altium Capital Management LP |
130,000
|
24.33 |
| Worth Venture Partners, LLC |
115,500
|
0.60 |
| Worth Venture Partners, LLC |
115,500
|
0.60 |
| Worth Venture Partners, LLC |
115,500
|
0.60 |
| QAAGZX - T. Rowe Price Health Sciences Portfolio
This fund is a listed as child fund of Price T Rowe Associates Inc /md/ and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
113,515
|
24.33 |
| Tri Locum Partners LP |
106,711
|
24.33 |
| Parallax Volatility Advisers, L.P. |
105,900
|
24.33 |
| HighVista Strategies LLC |
98,094
|
24.33 |
| Parkman Healthcare Partners LLC |
97,082
|
24.33 |
| Brighthouse Funds Trust II - T.Rowe Price Small Cap Growth Portfolio Class A |
95,749
|
24.33 |
| Group One Trading, L.p. |
92,700
|
24.33 |
| EAM Investors, LLC |
90,079
|
24.33 |
| DSMFX - Destinations Small-Mid Cap Equity Fund Class I |
85,051
|
20.78 |
| Mirabella Financial Services Llp |
84,851
|
79.67 |
| Connor, Clark & Lunn Investment Management Ltd. |
84,198
|
24.34 |
| HISCX - Hartford Small Cap Growth Hls Fund Ia |
81,990
|
24.33 |
| Brighthouse Funds Trust I - JPMorgan Small Cap Value Portfolio Class A |
72,567
|
24.34 |
| NORTHWESTERN MUTUAL SERIES FUND INC - Small Cap Growth Stock Portfolio |
70,909
|
24.33 |
| COLUMBIA FUNDS VARIABLE INSURANCE TRUST - Columbia Variable Portfolio - Small Company Growth Fund Class 1 |
66,763
|
24.32 |
| Endurant Capital Management LP |
64,704
|
24.33 |
| Caption Management, LLC |
63,000
|
24.33 |
| MMGEX - MassMutual Select Small Cap Growth Equity Fund Class A |
62,905
|
24.32 |
| ExodusPoint Capital Management, LP |
62,666
|
0.03 |
| TSCIX - AMG TimesSquare Small Cap Growth Fund Class Z |
60,000
|
24.33 |
| VVSCX - Small Cap Value Fund |
55,683
|
20.78 |
| GSCYX - SMALL CAP EQUITY FUND Institutional |
54,800
|
24.32 |
| John Hancock Funds II - Health Sciences Fund Class NAV |
54,190
|
20.78 |
| Chartwell Investment Partners, Llc |
53,720
|
0.02 |
| COLUMBIA FUNDS VARIABLE INSURANCE TRUST - Columbia Variable Portfolio - Small Cap Value Fund Class 1 |
53,120
|
24.32 |
| TRANSAMERICA SERIES TRUST - Transamerica T. Rowe Price Small Cap VP Initial |
53,042
|
24.34 |
| Bellevue Group AG |
52,900
|
24.33 |
| Laurion Capital Management LP |
50,805
|
24.33 |
| VCSLX - Small Cap Index Fund |
49,615
|
20.78 |
| CenterBook Partners LP |
48,284
|
24.34 |
| DMCRX - Driehaus Micro Cap Growth Fund |
47,722
|
24.33 |
| JEHSX - Health Sciences Trust NAV |
47,467
|
24.33 |
| Neuberger Berman Group LLC |
42,896
|
24.34 |
| RBB FUND, INC. - Adara Smaller Companies Fund |
42,631
|
20.78 |
| Jefferies Group LLC |
40,000
|
17.95 |
| NBMIX - Neuberger Berman Small Cap Growth Fund Investor Class |
37,330
|
20.79 |
| Engineers Gate Manager LP |
35,872
|
24.34 |
| EQ ADVISORS TRUST - EQ/T. Rowe Price Health Sciences Portfolio Class IB |
33,232
|
24.34 |
| Principal Financial Group Inc |
31,848
|
24.33 |
| PUTNAM VARIABLE TRUST - Putnam VT Global Health Care Fund Class IA Shares |
30,493
|
24.33 |
| MID - American Century Mid Cap Growth Impact ETF
This fund is a listed as child fund of American Century Companies Inc and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
28,025
|
20.77 |
| JESIX - Small Cap Index Trust NAV |
27,776
|
24.34 |
| SPWIX - Simt Small Cap Growth Fund Class I |
25,785
|
24.32 |
| NATIONWIDE VARIABLE INSURANCE TRUST - NVIT Multi-Manager Small Company Fund Class I |
25,072
|
24.33 |
| ORSIX - NORTH SQUARE DYNAMIC SMALL CAP FUND CLASS I |
25,050
|
20.80 |
| Jennison Associates Llc |
22,268
|
24.34 |
| AIM VARIABLE INSURANCE FUNDS (INVESCO VARIABLE INSURANCE FUNDS) - INVESCO V.I. Health Care Fund Series I |
21,198
|
24.34 |
| ASMOX - AQR Small Cap Momentum Style Fund Class I |
21,156
|
24.34 |
| ICSAX - VY(R) Columbia Small Cap Value II Portfolio Class ADV |
21,000
|
24.33 |
| Harvest Investment Services, LLC |
20,953
|
24.34 |
| NATIONWIDE VARIABLE INSURANCE TRUST - NVIT Multi-Manager Small Cap Growth Fund Class I |
20,436
|
24.32 |
| SLLAX - SIMT Small Cap Fund Class F |
19,888
|
24.34 |
| EQ ADVISORS TRUST - 1290 VT Micro Cap Portfolio Class IB |
19,304
|
24.35 |
| Neo Ivy Capital Management |
17,910
|
|
| Aevitas Wealth Management, Inc. |
17,773
|
21.44 |
| PENN SERIES FUNDS INC - Small Cap Growth Fund |
15,554
|
24.30 |
| DnB Asset Management AS |
13,770
|
24.33 |
| Rothschild Investment Corp /il |
12,200
|
|
| Stifel Financial Corp |
11,975
|
24.30 |
| Raymond James & Associates |
10,968
|
24.34 |
| Calvert Variable Products, Inc. - Calvert VP Russell 2000 Small Cap Index Portfolio - I Class |
10,767
|
24.33 |
| Teachers Retirement System Of The State Of Kentucky |
10,669
|
|
| VFMO - Vanguard U.S. Momentum Factor ETF ETF Shares
This fund is a listed as child fund of Vanguard Group Inc and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
10,332
|
20.81 |
| PEAK6 Investments LLC |
10,000
|
24.30 |
| DFAU - Dimensional US Core Equity Market ETF |
9,276
|
23.07 |
| SECAX - SIIT Small Cap II Fund - Class A |
9,071
|
20.73 |
| MMBUX - MassMutual Select T. Rowe Price Small and Mid Cap Blend Fund Class I |
8,476
|
24.30 |
| Walleye Trading LLC |
8,000
|
24.38 |
| SLPAX - Siit Small Cap Fund - Class A |
7,802
|
20.76 |
| CWSGX - Carillon Chartwell Small Cap Growth Fund Class Chartwell |
7,543
|
24.39 |
| TIFF INVESTMENT PROGRAM - TIFF Multi-Asset Fund |
6,483
|
24.37 |
| PAEAX - Putnam Dynamic Asset Allocation Growth Fund Class A shares |
6,046
|
24.31 |
| THRIVENT SERIES FUND INC - Thrivent Partner Healthcare Portfolio Class A |
5,840
|
24.32 |
| Great West Life Assurance Co /can/ |
5,372
|
|
| Toth Financial Advisory Corp |
5,000
|
24.40 |
| Virtus ETF Advisers LLC |
4,539
|
24.23 |
| VARIABLE INSURANCE PRODUCTS FUND II - Extended Market Index Portfolio Initial Class |
4,265
|
24.38 |
| PABAX - Putnam Dynamic Asset Allocation Balanced Fund Class A shares |
4,199
|
24.29 |
| MXMTX - Great-West Small Cap Growth Fund Investor Class |
3,965
|
24.21 |
| Dark Forest Capital Management Lp |
3,730
|
24.40 |
| Allspring Global Investments Holdings, LLC |
3,325
|
24.36 |
| HELX - Franklin Genomic Advancements ETF |
3,135
|
24.24 |
| GMSMX - GuideMark(R) Small/Mid Cap Core Fund Service Shares |
1,089
|
23.88 |
| PBSM - Invesco PureBeta MSCI USA Small Cap ETF
This fund is a listed as child fund of Invesco Ltd. and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
1,050
|
20.95 |
| Cutler Group LP |
1,000
|
|
| Cutler Group LP |
1,000
|
|
| PACAX - Putnam Dynamic Asset Allocation Conservative Fund Class A shares |
851
|
24.68 |
| SEASONS SERIES TRUST - SA Putnam Asset Allocation Diversified Growth Portfolio Class 1 |
496
|
24.19 |
| Crewe Advisors LLC |
452
|
24.34 |
| TCI Wealth Advisors, Inc. |
451
|
24.39 |
| MMSC - First Trust Multi-Manager Small Cap Opportunities ETF
This fund is a listed as child fund of First Trust Advisors Lp and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
337
|
20.77 |
| Humankind Benefit Corp - Humankind US Stock ETF |
222
|
22.52 |
| Washington Trust Advisors, Inc. |
59
|
16.95 |
| Wipfli Financial Advisors Llc, |
39
|
|
| Belpointe Asset Management LLC |
10
|
|
| Ameritas Advisory Services, LLC |
8
|
|
| Vivo Capital IX, LLC |
|
| Affinity Asset Advisors, LLC |
|
| Tamarack Advisers, LP |
|
| Gyon Technologies Capital Management, LP |
|
| Advanced Series Trust - Ast Prudential Growth Allocation Portfolio |
|
| Parametrica Management Ltd |
|
| Integral Health Asset Management, LLC |
|
| Nomura Asset Management Co Ltd |
|
| Brown Advisory Inc |
|
| Old Mission Capital Llc |
|
| USVM - VictoryShares USAA MSCI USA Small Cap Value Momentum ETF |
|
| Cheyne Capital Management (UK) LLP |
|
| Rockefeller Capital Management L.P. |
|
| Orbimed Advisors Llc |
|
| Venture Visionary Partners LLC |
|
| AZBAX - AllianzGI Small-Cap Fund Class A |
|
| Quantamental Technologies LLC |
|
| Axa S.a. |
|
| Brown Brothers Harriman & Co |
|
| Alphacrest Capital Management Llc |
|
| Winton Capital Group Ltd |
|
| PERCEPTIVE ADVISORS LLC |
|
| Commodore Capital Lp |
|
| Fred Alger Management, Llc |
|
| Fox Run Management, L.l.c. |
|
| Cna Financial Corp |
|
| Allegheny Financial Group LTD |
|
| Artal Group S.A. |
|
| Eversept Partners, LP |
|
| Toronto Dominion Bank |
|
| RidgeWorth Capital Management LLC |
|
| Sio Capital Management, LLC |
|
| Seven Eight Capital, Lp |
|
| Cowen And Company, Llc |
|
| Gsa Capital Partners Llp |
|
| GSATX - Goldman Sachs Small Cap Value Insights Fund Class A |
|
| Moody Aldrich Partners Llc |
|
| Alyeska Investment Group, L.P. |
|
| FRTY - Alger Mid Cap 40 ETF |
|
| Goldstream Capital Management Ltd |
|
| Frazier Life Sciences Management, L.P. |
|
| NPSGX - NICHOLAS PARTNERS SMALL CAP GROWTH FUND Institutional Shares |
|
| Rtw Investments, Lp |
|
| Silverarc Capital Management, Llc |
|
| Quantbot Technologies LP |
|
| Hrt Financial Lp |
|
| Lion Point Capital, LP |
|
| High Net Worth Advisory Group LLC |
|
| Adviser Investments LLC |
|
| RTW INVESTMENTS, LP |
|
| HealthCor Management, L.P. |
|
| Macquarie Group Ltd |
|
| Dupont Capital Management Corp |
|
| Norges Bank |
|
| Ellevest, Inc. |
|
| SA FUNDS INVESTMENT TRUST - SA U.S. Small Company Fund |
|
| STATE STREET CORP |
|
| Flynn James E |
|
| Point72 Hong Kong Ltd |
|
| Proequities, Inc. |
|
| VANGUARD GROUP INC |
|
| Aquatic Capital Management LLC |
|
| Bayesian Capital Management, LP |
|
| Trexquant Investment LP |
|
| Atom Investors LP |
|
| McElhenny Sheffield Capital Management, LLC |
|
| Quadrant Capital Group Llc |
|
| Y-Intercept (Hong Kong) Ltd |
|
| Bluefin Capital Management, Llc |
|
| Westwood Holdings Group Inc |
|
| DLD Asset Management, LP |
|
| Belvedere Trading LLC |
|
| Acadian Asset Management Llc |
|
| Boulder Hill Capital Management Lp |
|
| Vivo Capital, LLC |
|
| Vectors Research Management, LLC |
|
| Glenmede Trust Co Na |
|
| Banque Pictet & Cie Sa |
|
| Pura Vida Investments, Llc |
|
| Seven Grand Managers, Llc |
|
| HAP Trading, LLC |
|
| DVSMX - Driehaus Small Cap Growth Fund Investor Share Class |
|
| ASCGX - Lisanti Small Cap Growth Fund |
|
| PIBAX - PGIM BALANCED FUND Class A |
|
| Money Concepts Capital Corp |
|
| Octagon Capital Advisors LP |
|
| Lisanti Capital Growth, LLC |
|
| Two Sigma Advisers, Lp |
|
| Virtus Investment Advisers, Inc. |
|
| Occudo Quantitative Strategies Lp |
|
| NATIONWIDE VARIABLE INSURANCE TRUST - NVIT GS Small Cap Equity Insights Fund Class Y |
|
| Blackstone Alternative Investment Funds - Blackstone Alternative Multi-Strategy Fund Class I
This fund is a listed as child fund of Blackstone Group Inc and if that institution has disclosed ownership in this security, then these positions will not be double counted when calculating total shares and total value
|
25.00 |