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| Institution | Shares | Value | Change |
|---|---|---|---|
| FARALLON CAPITAL MANAGEMENT LLC | 5,781,066 | $232,051,989 | 0.00% |
| VANGUARD GROUP INC | 5,604,876 | $224,979,722 | 0.00% |
| BlackRock, Inc. | 4,545,738 | $182,465,924 | 0.00% |
| Bellevue Group AG | 3,714,736 | $149,109,503 | 0.00% |
| Erste Asset Management GmbH | 2,764,900 | $108,577,623 | 0.00% |
| Paradigm Biocapital Advisors LP | 2,673,555 | $107,316,498 | 0.00% |
| WELLINGTON MANAGEMENT GROUP LLP | 2,471,416 | $99,202,637 | 0.00% |
| Commodore Capital LP | 2,338,287 | $93,858,840 | 0.00% |
| STATE STREET CORP | 2,262,712 | $90,825,260 | 0.00% |
| MACQUARIE GROUP LTD | 1,958,101 | $78,598,000 | 0.00% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,656,938 | $66,510 | 0.00% |
| TCG Crossover Management, LLC | 1,430,041 | $57,401,846 | 0.00% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,416,315 | $56,859,764 | 0.00% |
| Frazier Life Sciences Management, L.P. | 1,279,754 | $51,369,326 | 0.00% |
| Caligan Partners LP | 1,131,205 | $45,406,569 | 0.00% |
| BANK OF AMERICA CORP /DE/ | 1,130,000 | $45,358,199 | 0.00% |
| DIMENSIONAL FUND ADVISORS LP | 1,021,201 | $40,987,144 | 0.00% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 987,339 | $39,631 | 0.00% |
| Caligan Partners LP | 975,000 | $39,136,500 | 0.00% |
| Rock Springs Capital Management LP | 958,542 | $38,475,876 | 0.00% |
| Institution | Action | Shares |
|---|---|---|
| Rockefeller Capital Management L.P. | BUY | 16,038 |
| Cloud Capital Management, LLC | BUY | 1 |
| AXA Investment Managers S.A. | BUY | 177,675 |
| TWO SIGMA ADVISERS, LP | BUY | 13,600 |
| Balyasny Asset Management L.P. | BUY | 495,491 |
| NORTHCAPE WEALTH MANAGEMENT, LLC | BUY | 5,240 |
| Jump Financial, LLC | BUY | 87,900 |
| HALBERT HARGROVE GLOBAL ADVISORS, LLC | BUY | 47 |
| ARIZONA STATE RETIREMENT SYSTEM | BUY | 16,255 |
| Freestone Grove Partners LP | BUY | 15,424 |
| QUADRANT CAPITAL GROUP LLC | BUY | 16 |
| Triumph Capital Management | BUY | 100 |
| Quarry LP | BUY | 5,000 |
| Y-Intercept (Hong Kong) Ltd | BUY | 7,932 |
| Cinctive Capital Management LP | BUY | 10,099 |
| FIRST HORIZON CORP | BUY | 1,124 |
| WINTON GROUP Ltd | BUY | 16,400 |
| Assenagon Asset Management S.A. | BUY | 67,153 |
| Parkman Healthcare Partners LLC | BUY | 100,380 |
| PEREGRINE CAPITAL MANAGEMENT LLC | BUY | 162,905 |
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